Dalle Scientific, LLC

We develop novel antiviral and antifungal biopesticides for protection of honey bees and greenhouse crops.

Our products are completely organic, biodegradable and safe for the honey bees and for the plants and crops.

They are completely free of live organisms.
They contain bacterial metabolites with powerful anti-viral and anti-fungal properties.
Our first product: BeeVirase -
anti-viral agent designed to protect honey bees from viral diseases.

BeeVirase is based on a cell-free supernatant enriched in endonuclease from a proprietary strain of bacterium Serratia marcescens (S. marcescens).


Our purification protocol removes the live bacteria and turns the BeeVirase into a stable product that is also safe for people, bees, and plants.


BeeVirase is being developed in collaboration with Giessen BioEngineering (Kazakhstan).


Giessen has developed the original Serratia endonuclease product and performed its field-based proof-of-concept testing. It was shown to markedly improve the health of bee colonies and increase the honey production.

Our products address a tremendous unmet need in agriculture for safe antiviral solutions to protect pollinators as well as plants and crops.
Honey bees contribute ~$15 billion a year to the U.S. agriculture by improving the harvesting yields and quality of the agricultural products.

Varroa mites are the greatest threat to the health of honey bees as they transmit several viruses which lead to severe diseases.

There are no effective antiviral medicines for honey bees on the market.
Endonuclease from Serratia marcescens has also been successfully applied in greenhouses and demonstrated both antiviral and anti-fungal properties.


Dalle Scientific's expertise:
Molecular biology
Genetic engineering
Bacterial fermentation
Virology

Protein chemistry
Formulation development
Manufacturing
Safety and efficacy testing
Honey bee pathogens
Honey bee physiology
Plant pathogens
Plant physiology
Our facilities:
Our laboratory is equipped with cell culture and fermentation equipment to allow the full range of experimental work from starting from in vitro all the way to pilot-scale bacterial and yeast fermentation capabilities.
Our team:
Dalle Scientific is led by a group of experienced professionals in the biotechnology, honey bee pathogens and physiology, agricultural product and business development.

  • Askar Kuchumov, Ph.D.
    Founder & CEO
    Entrepreneurial executive and project manager, with 20+ years’ experience across life sciences, drug development and venture capital industries.
  • Wei-Fone Huang, Ph.D.
    Lead Scientist
    Dr. Wei-Fone Huang brings more than 20 years of academic experience in researching honey bees and their pathogens. An expert entomologist and molecular biologist, he facilitates development of cutting-edge agricultural products at Dalle Scientific.
  • Zachary Huang, Ph.D.
    Scientific Consultant (honey bee physiology)
    Dr. Zachary Huang is a recognized expert in the field of honey bee behavior, physiology and molecular biology, and effects of biotic and abiotic stress factors on the health of bees. He has over 100 publications and is currently a professor at the Department of Entomology at Michigan State University.

Contacts:

ark@astrotide.com
+1-734-358-8521
Dalle Scientific, LLC
46701 Commerce Center Drive, Plymouth, Michigan 48170
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